Showing posts with label Easytan Europe. Show all posts
Showing posts with label Easytan Europe. Show all posts

Sunday, 17 November 2013

How to Use Melanotan 2

Mixing the solution
Flip off the cap from the Melanotan 2 vial.
Wipe the surface of the top of the vial with the enclosed alcohol wipe and discard the wipe.
For 10 & 20mg you will have glass vials with rubber stoppers to insert your needle into to draw the water out
For 30mg and above, wipe the surface of the injectable water tube with the enclosed alcohol wipe and discard the wipe.
Remove the enclosed syringe from the packaging. Making sure the injectable water tube is upright, insert the needle of the syringe into the sidewall of the water.
Now pull back the plunger of the syringe so you withdraw 1ml or 100 units of water and slowly pull the syringe out.
Insert the syringe into the Melanotan 2 vial and depress the plunger so you completely empty the syringe of the water and slowly remove the syringe from the vial.  Do not shake the solution.
Place the Melanotan 2 solution in the fridge for storage until ready for use.
Make sure you put the syringe caps on and carefully dispose of it.
You have now mixed your Melanotan 2 solution. Please store the solution in the fridge.



Administering the Melanotan 2
Select a new syringe and pull the plunger right back to the maximum mark.
Holding the Melanotan 2 vial upright, insert the syringe and depress the plunger fully (this is to equalise the air pressure in the vial which makes it easier to take out the Melanotan 2).
Leaving the syringe in the Melanotan 2 vial, turn everything upside down.
Pull the plunger until you have 10 units of Melanotan 2 in the syringe and slowly remove it.
Find a fleshy area of your skin - 4cm to the side of your belly button is the most common.  Wipe the area with one of the alcohol wipes included.
Pinch 2cm either side of the area to be injected.
Holding the syringe like a pen, and at 90 degrees to your skin, swiftly insert the syringe into your skin.
Fully depress the plunger so all the Melanotan 2 has emptied from the syringe and slowly withdraw.
Hold the alcohol wipe on the injected area for a minute.
You have now administered your first dose of Melanotan 2.

Dose frequency
From our own personal experiences, and from comments from our customers, we recommend that you carry out your Melanotan 2 injections just before you go to bed.  This will make the initial side effects less noticeable.

To enable your body to get used to the Melanotan 2 entering your body, we recommend new users of Melanotan 2 to inject half the amount to enable your body to get used to it.  Do this every other day until you have administered four doses of Melanotan 2.  Now you can administer the full dosage of Melanotan 2.

Keep injecting Melanotan 2 every other day and have one to two sunbed sessions a week until you have the colour that you desire.

Once you have the colour that you truly desire, you only need administer one dose of Melanotan 2 per week.  Sunbed sessions are only required once every other week.

You are now the envy of all your friends !!

What is Melanotan 2?

Melanotan 2 (otherwise known as MT2) was first synthesized at the University of Arizona.  Researches there knew that onc of the best defenses against skin cancer was melanin activated in the skin, a tan.  They hypothesized that an effective way to reduce skin cancer rates in people would be to induce the body's natural pigmentary system to produce a protective tan prior to UV exposure.  The body's naturally occuring hormone MSH causes melanogenesis, a process by which the skin's pigment cells (melanocytes) produce the skin's pigment (melanin).  They tested to see if administering this endogenous hormone to the body directly could be an effective method to cause sunless tanning.  What they found was that while it appeared to work, natural MSH had too short a half life in the body to be practical as a therapeutic drug.  So they decided to find a more potent and stable alternative, one that would be more practical.

After synthesizing and screening hundreds of molecules, the researchers headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7] MSH, that was approimately 1,000 times more potent than the natural MSH.  They dubbed this new peptide molecule, "Melanotan" (later Melanotan-1, now know as afamelanotide).  They subsequently developed another analog, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they called "Melanotan II".  The scientists hoped to use these peptides to combat melanoma by stimulating the body's natural pigmentary mechanism to create a tan without first needing exposure to harmful levels of UV radiation.  This in turn, they hypothesized, could reduce the potential for skin damage that can eventually lead to skin cancer.

A pilot phase I clinical trial conducted on three males by the College of Medacine, Pharmacology Department, University of Arizona in Tuscon, Arizona pulished in 1996 reported that, "Melanotan II has tanning activity in humans given only 5 low doses every other day by subcutaneous injection."  The side effects reported were mild nausea and a "stretching and yawning complex" that correlated with spontaneous penile erections.

The Department of Pharmacology, University of Arizona College of Medacin published in 1998 that involved 10 men who suffered from psychogenic erectile dysfunction.  Their trial concluded that, "Melanotan II is a potent initiator of erections in men with pyschogenic erectile dydfunction and has manageable side effects at a dose of 0.025mg/kg.

A clinical study published in 2000 of 20 men with psychogenic and organic erectile dysfunction conducted at the Section of Urology of The University of Arizona College of Medacin concluded, "that Melanotan II is a potent initiator of penile erection in men with ecrectile dysfunction.